GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs1577917 | 1 | rs6923148 | chr6:86767786 | SNHG5 | chr6:86386726-86388451:- | 0.56 | 9.97 | 5.7E-21 | Response to antipsychotic treatment |
| BLCA | cis | rs6927188 | 1 | rs6927188 | chr6:42912589 | PEX6 | chr6:42931613-42946981:- | -0.58 | -8.09 | 8.22E-15 | Diabetic kidney disease |
| BLCA | cis | rs6932590 | 1 | rs6932590 | chr6:27248931 | BTN3A2 | chr6:26365398-26378546:+ | -0.23 | -4.06 | 5.87E-5 | Schizophrenia |
| BLCA | cis | rs12529514 | 1 | rs6932936 | chr6:14115090 | CD83 | chr6:14117865-14137146:+ | -0.3 | -3.9 | 0.000113 | Rheumatoid arthritis |
| BLCA | cis | rs1577917 | 1 | rs6933377 | chr6:86705255 | SNHG5 | chr6:86386726-86388451:- | 0.46 | 8.31 | 1.7E-15 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs6936048 | chr6:86702608 | SNHG5 | chr6:86386726-86388451:- | -0.5 | -8.78 | 5.32E-17 | Response to antipsychotic treatment |
| BLCA | cis | rs568617 | 1 | rs693824 | chr11:65654783 | CTSW | chr11:65647284-65651212:+ | -0.6 | -9.06 | 6.99E-18 | Crohn's disease |
| BLCA | cis | rs568617 | 1 | rs693824 | chr11:65654783 | SNX32 | chr11:65601410-65621170:+ | 0.34 | 4.75 | 2.91E-6 | Crohn's disease |
| BLCA | cis | rs1577917 | 1 | rs6940458 | chr6:86644992 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -9.16 | 3.09E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs2243480 | 1 | rs6949812 | chr7:65387101 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.47 | 1.02E-5 | Diabetic kidney disease |
| BLCA | cis | rs568617 | 1 | rs694994 | chr11:65653309 | CTSW | chr11:65647284-65651212:+ | -0.6 | -9.14 | 3.8E-18 | Crohn's disease |
| BLCA | cis | rs568617 | 1 | rs694994 | chr11:65653309 | SNX32 | chr11:65601410-65621170:+ | 0.34 | 4.75 | 2.83E-6 | Crohn's disease |
| BLCA | cis | rs2243480 | 1 | rs6958289 | chr7:65657111 | CCT6P1 | chr7:65216092-65228661:+ | -0.35 | -4.75 | 2.86E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs6958420 | chr7:65751171 | CCT6P1 | chr7:65216092-65228661:+ | -0.35 | -4.72 | 3.27E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs6959002 | chr7:65650496 | CCT6P1 | chr7:65216092-65228661:+ | -0.35 | -4.71 | 3.52E-6 | Diabetic kidney disease |